Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)1990-472XФедеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации790310.18499/1990-472X-2022-0-89-23-27Original ArticlePHYTOPHARMACOLOGY OF WORMWOOD HERBAbramyanA. ADepartment of Pharmacology-KuzmenkoN. YDepartment of Pharmacology-Voronezh State Medical University1512202289232728102022Copyright © 2022, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)2022The features of the mechanism of action of wormwood herb, which are based on the ability to increase the activity of the gastric and intestinal glands, activate the secretion of bile, have been studied. The relationship between the chemicals that are part of wormwood and the field of application of this plant has been determined. Thus, absintin (bitterness) causes its use in diseases of the gastrointestinal tract, and essential oils (abinetol and pinene) contribute to the improvement of neuromuscular transmission. Based on the data of the state register of medicines, the main indications for the use of wormwood herb as a complex therapy of hypoacid conditions and hyporexia, as well as chronic cholecystitis, biliary dyskinesia were determined, methods of preparing infusion and tincture - the easiest to use dosage forms were studied, dosage regimens were determined.wormwood bittercholeretic effecttinctureполынь горькаяжелчегонное действиенастойка1.Cмaгинa, T.A. Bыдeлeниe биoлoгичecки aктивныx вeщecтв пoлыни гopькoй /T.A. Cмaгинa, Б.H. Бeкeтoв // Aктyaльн. пpoбл. фapм. Зaп. Cибиpи и Уpaлa. - Cвepдлoвcк. - 2020. - C. 63-67.2.Гpибeль, H.B. 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