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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-id><journal-title-group><journal-title>Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-title></journal-title-group><issn publication-format="electronic">1990-472X</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">6625</article-id><article-id pub-id-type="doi">10.18499/1990-472X-2020-0-80-3-9</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>DERMATOLOGICAL ASPECTS OF POLYCYSTIC OVARY SYNDROME IN THE FIRST TRIMESTER OF PREGNANCY</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Enkova</surname><given-names>V. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Olina</surname><given-names>A. A</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Dontsova</surname><given-names>E. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Khoperskaya</surname><given-names>O. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronezh State Medical University</aff><aff id="aff-2">Research Institute of obstetrics, gynecology and reproduction. D.O. Otta</aff><pub-date date-type="epub" iso-8601-date="2020-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2020</year></pub-date><issue>80</issue><fpage>3</fpage><lpage>9</lpage><history><pub-date date-type="received" iso-8601-date="2021-03-16"><day>16</day><month>03</month><year>2021</year></pub-date></history><permissions><copyright-statement>Copyright © 2020, Научно-медицинский вестник Центрального Черноземья</copyright-statement><copyright-year>2020</copyright-year></permissions><abstract>The relevance of studying dermatological manifestations of excess androgens is due to three main factors: the widespread and steady growth of hyperandrogenic conditions, the psychotraumatic effect of reflection in the mirror on the patient, and the potential threat of a serious endocrine disorder, for which external manifestations are only the peak of the iceberg. The research studied dermatological manifestations in pregnant patients with polycystic ovary syndrome, as well as their relationship with indicators of carbohydrate metabolism, micronutrient status, and women's psycho-emotional state. Data analysis showed that the dermatological aspect is a significant cause of psycho-emotional disorders in patients with polycystic ovary syndrome. The reasons that lead to such mental disorders are clear: cosmetic manifestations of the disease, excess body weight or obesity, irregular menstrual cycle, infertility, the threat of gestational complications, as well as unpleasant long-term consequences of endocrinopathy. Pregnant patients with normal indicators of metabolism and micronutrient status have a lower frequency and severity of skin manifestations of the disease, as well as low rates of neurotism, anxiety and depressive disorders, which indicates the need for mandatory pregravidar training.</abstract><kwd-group xml:lang="en"><kwd>polycystic ovary syndrome</kwd><kwd>pregnancy</kwd><kwd>androgen-dependent dermopathies</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>синдром поликистозных яичников</kwd><kwd>беременность</kwd><kwd>андрогензависимые дермопатии</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Богатырева, Е. М. Лечение девушек-подростков с синдромом поликистозных яичников и инсулинорезистентностью / Е. М. Богатырева, Г. А. Новик // Бюллетень сибирской медицины. - 2018. - Т. 17, № 2. - С. 13-20.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Довженко, Т. В. 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