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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-id><journal-title-group><journal-title>Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-title></journal-title-group><issn publication-format="electronic">1990-472X</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">5062</article-id><article-id pub-id-type="doi">10.18499/1990-472X-2017-0-69-79-84</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>EXPERIENCE OF TREATMENT OF INFANTILES HEMANGIOMAS OF THE MAXILLO-FACIAL AREA IN CHILDREN WITH USE PROPRANOLOL</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Garshina</surname><given-names>M A</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Korytina</surname><given-names>I V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kharitonov</surname><given-names>D YU</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronezh State Medical University</aff><pub-date date-type="epub" iso-8601-date="2017-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2017</year></pub-date><issue>69</issue><fpage>79</fpage><lpage>84</lpage><history><pub-date date-type="received" iso-8601-date="2020-04-25"><day>25</day><month>04</month><year>2020</year></pub-date></history><permissions><copyright-statement>Copyright © 2017, Научно-медицинский вестник Центрального Черноземья</copyright-statement><copyright-year>2017</copyright-year></permissions><abstract>The issues of the efficacy and safety of treatment of children with infantile hemangiomas of the maxillo facial area with non-selective Β-adrenoblockers. Hemangiomas occupy the first place in the frequency of occurrence among benign neoplasms in children. It should be clinically identified infantile hemangiomas, consisting mainly of immature endothelium of the vessels, which can be treated with non-selective β-adrenoblockers. Therefore, the selection of patients should be thorough and considered. The article reflects the experience of complex treatment of 13 patients with infantile hemangiomas of the face and neck. All have achieved an improvement in the local status and there are no serious complications. During the course of treatment, a pediatric patronage monitoring, self-sustaining (home-made) pulse and blood pressure control and monthly blood glucose monitoring, ECG and cardiologist consultation are required.</abstract><kwd-group xml:lang="en"><kwd>Infantile hemangioma</kwd><kwd>propranolol</kwd><kwd>treatment</kwd><kwd>children</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инфантильная гемангиома</kwd><kwd>пропранолол</kwd><kwd>лечение</kwd><kwd>дети</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Бензар И.Н. Лечение инфантильных гемангиом у детей: более консервативный подход // Медицина и образование в сибири. 2014; 1: 23с</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Буторина А.В., Поляев Ю. А. Новые технологии в лечении гемангиом кожи у детей // Детская больница. - М., 2001.- № 1. - С. 44-48.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Котлукова Н.П., Рогинский, В.В., Тимофеева, М.Ю. и др. Новый взгляд на лечение инфантильных гемангиом и сосудистых гиперплазий препаратом пропранолол // Педиатрия. - 2012. - Т.91.- №6. - С.60-64.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Кучеров Ю. И., Жиркова Ю. В., Гетман А. Н., Ивлева С. А., Рехвиашвили М. Г. Клинический случай лечения пропранололом гемангиомы печени у новорожденного. Вестник Российской академии медицинских наук. 2014; 5-6: 81-85.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Нурмеев И.Н., Осипов Д.В., Шаммасов Р.З. Особенности и современные возможности нехирургического лечения осложненных гемангиом у детей. Онкопедиатрия. 2014; 4: 49 - 51.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Поляев Ю. А., Постников С. С., Мыльников А. А., Гарбузов Р. В., Нарбутов А. Г., Шимановский Н. Л. Новые возможности в лечении инфантильных гемангиом с помощью пропранолола. Международный медицинский журнал. 2012; 2: 94-103.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Drolet B.A., Frommelt P.C., Chamlin S.L., Haggstrom A., Bauman N.M. et al. Initiation and use of propranolol for infantile hemangioma: Report of a consensus conference. Pediatrics. 2013; 131 (1): 128-140.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Leaute-Labreze C., Dumas de la Roque E., Hubiche T. et al. Propranolol for Severe Hemangiomas of Infancy. New England Journal of Medicine. 2008; 358 (24): 2649-2651.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Leaute-Labreze C., Prey S., Ezzedine K. Infantile hemangioma: part II: Risks, complications and treatment. Journal of the European Academy of Dermatology and Venerology. 2011; 25: 1254-1260.</mixed-citation></ref></ref-list></back></article>
