Научно-медицинский вестник Центрального ЧерноземьяНаучно-медицинский вестник Центрального Черноземья1990-472XФедеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации1165210.18499/1990-472X-2026-27-2-68-73Features of the clinical course of post-infarction cardiosclerosis in patients undergoing a new coronavirus infection COVID-19vjcrdf35@mail.rugospterap@vrngmu.ruVoronezh State Medical University named after N.N. Burdenko30062026272687305072026Copyright © 2026, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)2026The most common cause of death, according to the WHO, is coronary heart disease (CHD). Despite the successful treatment of acute forms of coronary artery disease using endovascular techniques, chronic forms of coronary artery disease continue to progress and invalidate the able-bodied population of the country. A pressing issue in the 21st century is the effect of infectious agents on the cardiovascular system. The high affinity of the structure of the SARS-CoV-2 virus for APF2, widely represented in many body systems, defines coronavirus infection as a disease with a diverse symptom complex and is of direct interest in studying the consequences of an infection. The purpose of the study: to assess the effect of the previous coronavirus infection COVID-19 on the course of post-infarction cardiosclerosis. Materials and methods: 74 patients took part in the study. Distribution into groups was carried out depending on the fact of the transferred NKVI. The main group of 40 men and 8 women with past NCVI, mean age 67.0 [61.0; 70.2] years, control group included 15 men and 11 women who did not have NCVI, mean age 64.0 [58.8; 69,8]. Statistical data processing was carried out using StatTech v. 4.12.1 and Microsoft Excel 2010. Results: patients with post-infarction cardiosclerosis belong mainly to the elderly age group, regardless of the history of COVID-19; patients who have recovered from COVID-19 and have concomitant diseases are more likely to develop an acute coronary event. Coronavirus infection contributes to a more severe course of post-infarction cardiosclerosis, expressed in the 6MKh test (p = 0.02) and significantly reduces the contractility of the left ventricle in these patients (p = 0.04).coronavirus infection, post-infarction cardiosclerosis, coronary heart diseaseкоронавирусная инфекция, постинфарктный кардиосклероз, ишемическая болезнь сердца