Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)1990-472XФедеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации1101010.18499/1990-472X-2025-26-3-59-65Аmplitude-integrated EEG in pediatric palliative patients with neuropsychiatric deficitGrechanayaSeverin Viacheslavovich<p>MD, Head of the Department of Psychiatry and Narcology</p>svgrechany@mail.ruKoshchavtsevAndrey Helievich<p>PhD, Associate Professor of the Department of Psychiatry and Narcology</p>mdspb@yandex.ruMitrochenkovaNatalya Nikolaevna<p>the psychiatrist</p>mitronata2011@mail.ruFederal State Budgetary Educational Institution of Higher Medical Education of the Ministry of Health of the Russian FederationS.S. Mnukhin Children's Psychiatry Rehabilitation Center10112025263596502102025Copyright © 2025, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)2025<p>The study included 33 pediatric palliative patients in the palliative care unit and 56 newborns in the intensive care units of the neonatal pathology department of a multidisciplinary children's hospital. Palliative patients have severe incurable diseases with a high risk of death. Among the palliative conditions associated with brain damage, the most common were severe forms of cerebral palsy, severe forms of organic brain damage, malignant epilepsy, and severe consequences of neuroinfections genetic syndromes. The average age of newborns was 20.0 days, and that of palliative patients was 6.9 years; the significance of differences was p=0.0001, meaning that the groups were statistically different. The newborns were preterm infants according to the clinical classification (average gestational age was 36 weeks). The medical history and neurological status were assessed. Computed tomography and ultrasound were used to diagnose individual brain lesions. All children underwent routine EEG with a tendency to monitoring research and further software amplitude-integrated (aEEG) processing. The EEG and aEEG indices in palliative patients generally do not differ from the indices in the comparison group consisting of newborn children. Consequently, the functional state of the brain of palliative patients of older childhood, which suffered as a result of organic damage (cerebral palsy, hydrocephalus, neuroinfections, apallic states, etc.) due to a kind of ontogenetic regression, resembles the functional state of the brain of newborn children (recorded using EEG, aEEG).</p>palliative patients, premature newborns, EEG analysis, amplitude-integrated EEG (aEEG), perinatal encephaiopathyпаллиативные пациенты, недоношенные новорожденные, оценка параметров аЭЭГ, показатели ЭЭГ, перинатальная энцефалопатия[1. Кощавцев А. Г. Интерпретация данных электроэнцефалографии у детей раннего возраста / А. Г. Кощавцев, С. В. Гречаный // Эпилепсия и пароксизмальные состояния. – 2020. – Т. 12, № 1. – С. 9-25. – DOI 10.17749/2077-8333.2020.12.1.9-25. – EDN BPUWBA.][2. 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