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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-id><journal-title-group><journal-title>Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-title></journal-title-group><issn publication-format="electronic">1990-472X</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">10785</article-id><article-id pub-id-type="doi">10.18499/1990-472X-2025-26-1-49-54</article-id><article-categories><subj-group subj-group-type="heading"><subject>Unclassified</subject></subj-group></article-categories><title-group><article-title>Clinical case: a patient with generalized atherosclerosis &#13;
and comorbid pathology</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Avdanina</surname><given-names>Daria</given-names></name><email>avdaninad@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Muravitskaya</surname><given-names>Marina</given-names></name><email>mnmuravitskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Pashkova</surname><given-names>Anna</given-names></name><email>apashkova@vrngmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Lagutina</surname><given-names>Svetlana</given-names></name><email>svlagutina97@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bugrovskaya</surname><given-names>Anna</given-names></name><email>annabvss@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1"></aff><pub-date date-type="epub" iso-8601-date="2025-03-28" publication-format="electronic"><day>28</day><month>03</month><year>2025</year></pub-date><volume>26</volume><issue>1</issue><fpage>49</fpage><lpage>54</lpage><history><pub-date date-type="received" iso-8601-date="2025-03-31"><day>31</day><month>03</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2025, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</copyright-statement><copyright-year>2025</copyright-year></permissions><abstract>&lt;p&gt;A portrait of a 72-year-old patient with generalized atherosclerosis, hypertension without achieving the target blood pressure level, coronary heart disease: atherosclerotic atherosclerosis, type 2 diabetes mellitus with target organ damage, CHF is presented. The patient's unwillingness to receive a large number of drugs, their high cost, ineffectiveness of hypolipidemic, planned hypotensive, disaggregant, hypoglycemic therapy of comorbid pathology for the purpose of individual prevention of ischemic stroke / myocardial infarction due to irregular drug intake led to the formation of generalized atherosclerosis, hemodynamically significant atherosclerosis of the right femoral, both popliteal arteries, right internal carotid artery, failure to achieve the target level Blood pressure, the appearance and progression of CHF. The patient has an extreme risk of cardiovascular complications, which can be realized at the present time, which dictates the need to review the pharmacotherapy of comorbid pathology.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>atherosclerosis, comorbid pathology, risk of cardiovascular complications, pharmacotherapy.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>атеросклероз, коморбидная патология, риск сердечно-сосудистых осложнений, фармакотерапия.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Алгоритмы специализированной медицинской помощи больным сахарным диабетом / Дедов И.И. [и др.] // Сахарный диабет. – 2023. - №26(2). - 236 с.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Артериальная гипертензия у взрослых: клинические рекомендации. - 2024. - с. 220 с.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>3. Нарушения липидного обмена: клинические рекомендации. - 2023. – 103 с.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>4. Нарушения липидного обмена в структуре коморбидной патологии: современные принципы диагностики, лечения и профилактики на амбулаторном этапе / М.Н. Муравицкая // Системный анализ и управление в биомедицинских системах. - 2024. - Т. 2. - № 2. - С. - 8-13.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>5. Сравнительная оценка рисков развития фаталь ных и нефатальных сердечно - сосудистых событий при использовании шкал SCORE/SCORE2 у пациентов с кардиоваскулярной патологией / С.Н. Лагутина // Научно-медицинский вестник Центрального Черноземья. – 2023. – Т. 24, № 3 (сквозной номер 93). - С. 52-60.</mixed-citation></ref></ref-list></back></article>
