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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-id><journal-title-group><journal-title>Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-title></journal-title-group><issn publication-format="electronic">1990-472X</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">10190</article-id><article-id pub-id-type="doi">10.18499/1990-472X-2024-25-4-73-78</article-id><article-categories><subj-group subj-group-type="heading"><subject></subject></subj-group></article-categories><title-group><article-title>Pathopfysiology of arterial hypertension in chronic kidney disease</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Nekrasova</surname><given-names>Светлана Vladimirovna</given-names></name><bio>&lt;p&gt;student&lt;/p&gt;</bio><email>vetanekras@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Makeeva</surname><given-names>Анна</given-names></name><bio>&lt;p&gt;&lt;span class="TextRun SCXW196149104 BCX0" lang="RU-RU" xml:lang="RU-RU" data-contrast="auto"&gt;&lt;span class="NormalTextRun SCXW196149104 BCX0"&gt;к.б.н., доцент кафедры патологической физиологии&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</bio><email>makeeva81@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bolotskikh</surname><given-names>Vladimir Ivanovich</given-names></name><bio>&lt;p&gt;MD, Professor, Head of the Department of Pathological Physiology&lt;/p&gt;</bio><email>patfiz@vrngmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Berezhnova</surname><given-names>Tatyana Alexandrovna</given-names></name><bio>&lt;p&gt;Doctor of Medicine, Professor, Head of the Department of Pharmacology&lt;/p&gt;</bio><email>berezhnova-tatjana@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Nekrasova</surname><given-names>Natalya Vasilevna</given-names></name><bio>&lt;p&gt;PhD, Associate Professor of the Department of Hospital Therapy and Endocrinology&lt;/p&gt;</bio><email>gospterap@vrngmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Babenko</surname><given-names>Nina Ivanovna</given-names></name><bio>&lt;p&gt;PhD, Assistant of the Department of Hospital Therapy and Endocrinology&lt;/p&gt;</bio><email>nibabenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Burdenko VSMU of the Ministry of Health of the Russian Federation</aff><pub-date date-type="epub" iso-8601-date="2024-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2024</year></pub-date><volume>25</volume><issue>4</issue><fpage>73</fpage><lpage>78</lpage><history><pub-date date-type="received" iso-8601-date="2025-01-09"><day>09</day><month>01</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2025, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</copyright-statement><copyright-year>2025</copyright-year></permissions><abstract>&lt;p&gt;&lt;span class="TextRun SCXW194290108 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"&gt;&lt;span class="NormalTextRun SCXW194290108 BCX0"&gt;Due to the fact that in modern clinical practice, doctors are increasingly faced with kidney disease of different origins, due to a set of concomitant pathologies such as arterial hypertension, diabetes mellitus, metabolic syndrome. In this regard, the influence of hypertension on the development of chronic kidney disease is of particular relevance. To date, it has been proven that: genetic factors, the presence and degree of albuminuria, high cholesterol, abdominal obesity, diabetes, the use of non-steroidal anti-inflammatory drugs, socio-economic factors, racial and ethnic differences, lifestyle are factors affecting the control and severity of hypertension. At the moment, this pathology is a global problem that affects the quality of life of people and mortality from the corresponding complications. When analyzing the statistical data of the Health Ministry of the Russian Federation, as well as other developed countries, we see an increase in morbidity and mortality from chronic kidney disease, especially in people over 60. According to forecasts, by 2025, the number of patients with arterial hypertension will increase to 1.5 billion people. In this regard, it is of interest to study the clinical case in order to extrapolate the idea of&lt;/span&gt;&lt;span class="NormalTextRun SCXW194290108 BCX0"&gt;&lt;/span&gt;&lt;span class="NormalTextRun SCXW194290108 BCX0"&gt; the interconnected pathogenetic effect of pathological phenomena on the patient's health.&lt;/span&gt;&lt;/span&gt;&lt;span class="EOP SCXW194290108 BCX0" data-ccp-props="{134245417:false,335551550:6,335551620:6,335559731:567,335559738:48,335559745:20}"&gt;&lt;/span&gt;&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>chronic kidney disease</kwd><kwd>cardiovascular diseases</kwd><kwd>hypertension</kwd><kwd>blood pressure</kwd><kwd>albuminuria.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>артериальная гипертензия</kwd><kwd>артериальное давление</kwd><kwd>альбуминурия.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. 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