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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-id><journal-title-group><journal-title>Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-title></journal-title-group><issn publication-format="electronic">1990-472X</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">10034</article-id><article-id pub-id-type="doi">10.18499/1990-472X-2024-25-1-%p</article-id><article-categories><subj-group subj-group-type="heading"><subject></subject></subj-group></article-categories><title-group><article-title>Effect of molecular hydrogen on severity of fatigue symptoms in students</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Chechelnitskaya</surname><given-names>Anastasia</given-names></name><email>i@achechelnitskaja.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>DIADINA</surname><given-names>Xenia</given-names></name><email>dyadina_2017@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Berezhnova</surname><given-names>Tatyana</given-names></name><email>berezhnova-tatjana@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Luneva</surname><given-names>Elena</given-names></name><email>e.a.luneva97@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1"></aff><pub-date date-type="epub" iso-8601-date="2024-04-13" publication-format="electronic"><day>13</day><month>04</month><year>2024</year></pub-date><volume>25</volume><issue>1</issue><fpage>29</fpage><lpage>33</lpage><history><pub-date date-type="received" iso-8601-date="2024-04-16"><day>16</day><month>04</month><year>2024</year></pub-date></history><permissions><copyright-statement>Copyright © 2024, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</copyright-statement><copyright-year>2024</copyright-year></permissions><abstract>&lt;p&gt;Chronic fatigue syndrome (CFS) is one of the most common pathologies to date, which is explained by frequent stress, fast pace of life, impaired biorhythms, and frequent overwork. Women are more likely to experience CFS than men, according to various sources, about 14% of young people aged 14 to 25 are susceptible to the development of this syndrome. Medical students often complain of constant fatigue, decreased concentration, impaired memory and attention. All these symptoms disrupt the quality of life, because students need to remember large amounts of information, be able to quickly answer the questions posed. To correct this condition, various methods are used, for example, mineral baths, correction of the daily regime, setting up a work and rest regime. Sometimes the use of these methods is impossible, while the use of water enriched with hydrogen is the simplest method of possible correction of this state.&lt;/p&gt;&#13;
&lt;p&gt;The aim of this work is to study the effect of water enriched in molecular hydrogen on chronic fatigue in students.&lt;/p&gt;&#13;
&lt;p&gt;Materials and methods. The study involved 45 volunteer students of the 3rd year of the Faculty of Medicine. The study lasted 21 days. All participants were divided into 3 groups of 15 people. The first study group received in addition to the usual diet plain water in a volume of 600 ml per day in three doses. The second group studied received in the same way as the first, water enriched with molecular hydrogen. The third group is control. In hydrogen water, the concentration of dissolved hydrogen was 0.8-1.1 ppm. On the first and last day of the study, students were tested to identify the degree of chronic fatigue.&lt;/p&gt;&#13;
&lt;p&gt;It was revealed that in the group receiving water enriched with molecular hydrogen, participants noted an improvement in mood and performance, an increase in attention, while reducing the severity of fatigue symptoms.&lt;/p&gt;&#13;
&lt;p&gt;In the 1st and 3rd groups, students, in general, did not notice an improvement in their condition.&lt;/p&gt;&#13;
&lt;p&gt;Intake of water enriched with molecular hydrogen helps to reduce the symptoms of chronic fatigue and improve well-being.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>molecular hydrogen</kwd><kwd>water enriched with molecular hydrogen</kwd><kwd>the antioxidant effect of hydrogen</kwd><kwd>chronic fatigue</kwd><kwd>chronic fatigue syndrome.Keywords: molecular hydrogen</kwd><kwd>water enriched with molecular hydrogen</kwd><kwd>UK antioxidant effect</kwd><kwd>chronic fatigue</kwd><kwd>fatigue syndrome.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>молекулярный водород</kwd><kwd>вода, обогащенная молекулярным водородом</kwd><kwd>антиоксидантный эффект водорода</kwd><kwd>хроническое утомление</kwd><kwd>синдром хронической усталости.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Dobashi S, Takeuchi K, Koyama K. Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males. Med Gas Res. 2020 Jan-Mar;10(1):21-26. doi: 10.4103/2045-9912.279979. PMID: 32189665; PMCID: PMC7871940.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Iida A, Nosaka N, Yumoto T, Knaup E, Naito H, Nishiyama C, Yamakawa Y, Tsukahara K, Terado M, Sato K, Ugawa T, Nakao A. The Clinical Application of Hydrogen as a Medical Treatment. Acta Med Okayama. 2016 Oct;70(5):331-337. doi: 10.18926/AMO/54590. PMID: 27777424.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>3. Yancey JR, Thomas SM. Chronic fatigue syndrome: diagnosis and treatment. Am Fam Physician. 2012 Oct 15;86(8):741-6. PMID: 23062157.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>4. Гусев, Е. И. Неврология : национальное руководство / Под ред. Е. И. Гусева, А. Н. Коновалова, В. И. Скворцовой, А. Б. Гехт. - Москва : ГЭОТАР-Медиа, 2016. - 1040 с. (Серия "Национальные руководства") - ISBN 978-5-9704-3620-2.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>5. Патент № 2256456 C1 Российская Федерация, МПК A61K 35/08, A61P 25/00. Способ коррекции нарушений адаптации у больных синдромом хронической усталости : № 2003130720/14 : заявл. 17.10.2003 : опубл. 20.07.2005 / М. П. Товбушенко, В. В. Анашкин, Н. А. Дидковский ; заявитель Государственное учреждение "Пятигорский государственный научно-исследовательский институт курортологии Министерства Здравоохранения Российской Федерации".</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>6. Рахманин Ю.А., Егорова Н.А., Михайлова Р.И., Рыжова И.Н., Каменецкая Д.Б., Кочеткова М.Г. Молекулярный водород: биологическое действие, возможности применения в здравоохранении (обзор). Гигиена и санитария . 2019;98(4):359-365. https://doi.org/10.47470/0016-9900-2019-98-4-359-365</mixed-citation></ref></ref-list></back></article>
